AI, NGT insects & gene drives

Various databases now provide access to the genetic material of numerous insect species. This genomic data can be searched and processed with AI programs in order to:

  • find target genes that are suitable for applications of insecticidal RNA in pests
  • identify regulatory sequences that can be used to interfere with gene regulation or specifically enhance the expression of certain genes
  • predict CRISPR/Cas outcomes in advance

New genetic engineering techniques are also being used to develop so-called ‘gene drives’ for use in a number of insect species. The gene drive method is used to produce genetically engineered organisms that enable the rapid spread of artificial gene constructs in subsequent generations, thus considerably outpacing natural inheritance. In this instance, AI is used, amongst other things, to assess the impact on target populations, or to identify suitable target genes which could be genetically engineered via ‘gene drives’.

Gene drives can trigger a mutagenic chain reaction in natural populations, amongst others, which can result in the extinction of the affected populations. Furthermore, if gene drive organisms are released, it is not unlikely that subsequent generations will exhibit undesirable traits that were not observed in the laboratory. If damage occurs, in many cases there will be only insufficient options to control or retrieve the organisms.

Publication date / last update:
March 2026